Primary Antibody Matched Pairs
Biotium S100A9 + Calprotectin (S100A8/A9 Complex)(MAC3157R), CF568 conjugate, 0.1mg/mL
Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including
Bioss NEK2 Monoclonal Antibody
NEK2 Primary Antibody Unconjugated Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Mouse TNF ELISA Pair Set 5PP (Sino Biological)
Each vial contains 68 ng of recombinant Mouse TNF-alpha / TNFA / TNFSF2 ELISA Pair Set. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 6000 pg/mL is recommended.
ABclonal Technology Phospho-AKT1-T308+AKT2-T309+AKT3-T305 Rabbit pAb
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
ABclonal Technology LDHC Rabbit pAb
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5 untranslated region.
Medchemexpress LLC LOX-1/OLR1 Human H 5ug
Recombinant human LOX-1/OLR1 extracellular domain expressed in HEK293 cells and supplied lyophilized with a C-terminal His tag. The protein is >95% pure by reducing SDS-PAGE, formulated in phosphate buffer with sodium chloride, and provided in a range of microgram to milligram sizes. Store lyophilized at -20°C; after reconstitution store short term at 4°C or aliquot and freeze at -20°C/-80°C for long-term storage. For research use only.
- Recombinant extracellular domain suitable for binding and biochemical assays.
- Expressed in mammalian cells with a C-terminal 6xHis tag to enable affinity purification.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Lyophilized from 20 mM PB, 150 mM NaCl, pH 7.2 for stability.
- Reconstitute at ≥100 μg/mL in ddH2O; aliquot and freeze for long-term storage.
- Intended for research use only.
Biotium CD55 (DAF)(143-30), CF740 conjugate, 0.1mg/mL
Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405
Biotium S100A9(47-8D3), Biotin conjugate, 0.1mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
ABclonal Technology NKX2-1 Rabbit mAb
This gene encodes a protein initially identified as a thyroid-specific transcription factor The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and may be associated with thyroid cancer Multiple transcript variants encoding different isoforms have been found for this gene This gene shares the symbol alias TTF1 with another gene transcription termination factor 1 which plays a role in ribosomal gene transcription
Biotium S100A9(47-8D3), CF568 conjugate, 0.1mg/mL
This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylate
Medchemexpress LLC CRABP2 protein, mouse (His-tag) | >95.0% | 50 UG
Recombinant His-tagged mouse cellular retinoic acid-binding protein 2 (CRABP2) supplied as a purified protein for biochemical and cell biology research. Expressed in E. coli and provided in microgram quantities, the protein is suitable for binding studies, assay development, and receptor interaction experiments.
- Greater than 95.0% purity as determined by reducing SDS-PAGE.
- Expressed in E. coli for recombinant protein production.
- N-terminal 6xHis tag for affinity purification and detection.
- Approximate molecular weight 16 kDa.
- Store at -20°C; aliquot and freeze at -20°C or -80°C for long-term storage.
- Datasheet, certificate of analysis, and safety documentation available.
Bioss KHSRP Recombinant Monoclonal A
KHSRP Primary Antibody Unconjugated Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB IHC-P IHC-F IF(ICC) IP IF RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
Medchemexpress LLC Guanylate-binding protein 1, human (HEK293, His) | >95.0% | 50 UG
Recombinant human guanylate-binding protein 1 expressed in HEK293 cells with a C-terminal His tag. Supplied as a 0.22 μm filtered PBS solution at high purity for research applications including enzymatic assays, binding studies, and antibody validation.
- Expressed in HEK293 mammalian cells.
- C-terminal 10xHis tag for purification and detection.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximate molecular weight ~65 kDa.
- Supplied in 0.22 μm filtered PBS, pH 7.4.
- Recommended storage at -80°C; avoid repeated freeze-thaw cycles.
- Available in small research sizes including 50 μg.
Sino Biological Anti-Bikunin/AMBP Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with purified, recombinant Human Bikunin/AMBP (rh Bikunin/AMBP; Catalog#13141-H08H1; NP_001624.1; Met1-Val203). Bikunin/AMBP specific IgG was purified by Human Bikunin/AMBP affinity chromatography.
Biotium Calprotectin / MRP14 / S100A9 / Calgranulin B(rMAC3781), 1mg/mL
Calprotectin is a heteroduplex of Protein S100-A8/A9 (also called MRP-8/14, or Calgranulin A/B). This antibody recognizes the 14 kDa B component (Protein S100-A9) of the complex. Protein S100-A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Altered expression of this protein is associated with the disease cystic fibrosis. This antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.